When bone resorption rates are higher than bone formation rates, the amount of bone mass decreases. Osteoporosis is caused by changes in bone metabolism as a result of menopause. When exposed to Ca-supplemented citric beverages on a regular basis, our hypothesis is that absorption acid promotes the absorption of this mineral. As a result, osteoblasts were likely unable to function, and bone formation was likely hampered. Normal levels of blood Ca in LECA group members suggest that bone does not need to provide this mineral. discovered a significant drop in TRACP-5b and BAP concentrations. After five months of intervention, the LECA group’s value was negative however, the LE and control groups’ value was positive.īoth groups had significantly lower levels of bone resorption and bone formation markers than the LECA and LE groups. The concentration of the bone resorption marker TRACP-5b had a significant interaction. Concentrations of the three subject groups were not significantly different in terms of BAP levels. In both cases, u-NTx levels were not significantly different between the LECA and control groups before and after the five-month intervention (Figure 2(d). There were no significant differences in TRACP-5b concentrations between all three subjects or between time periods. In the presence of investigational products, changes in the BMD of the lumbar spine and femur are associated with the products. The significance level of the tests was determined by taking into account the levels of significance determined by p. The net gain in BMD for each group was calculated by subtracting the pre-intervention BMD from the BMD that was detected after five months of intervention.įollowing the Dunnett multiple comparison test, an analysis of variance obtained by one-way comparison was performed. The distributions of BMD values and bone metabolism marker levels were normality tested by histograms and the Kolmogorov-Smirnov test (p = 0.200). Individuals who consumed an average of 30 mL of lemon per day (about 30 mL per day on average) had lower blood pressure. Ca is currently recommended to be consumed in amounts ranging from 700 mg to 1350 mg per day in adult women. The levels of Ca and lemon juice in the investigational products were within the ranges of those found in normal foods. A physical evaluation, as well as bone mineral density and bone metabolism markers, were performed. The subjects were matched based on their age and body mass index (BMI).Įach subject in the LECA and LE groups consumed one serving (260 mL) of an investigational product every five months for the duration of the study. The study, which lasted from December 2015 to June 2016, was completed. As a result, the concentration of the bone resorption marker tartrate-resistant acid phosphatase 5b (TRACP-5b) decreased significantly one month after study initiation but remained constant the following month. In 2015, we investigated whether drinking lemon drinks supplemented with Ca would help with bone metabolism in postmenopausal women. Citric acid, a type of organic acid, acts as a chelating agent and aids in the absorption of minerals such as calcium and iron. Following that, levels of Ca in the blood increase, preventing the release of PTH and, as a result, decreasing the production of 1,25-(OH)2 D3. PTH sensitivity is increased in postmenopausal women with osteoporosis as a result of decreased estrogen levels, and bone resorption is increased. If you’re concerned about your bone health, you may want to limit your intake of lime juice. However, more research is needed to confirm these findings. So, there is some evidence that lime juice may be bad for your bones. This means that their bones were weaker and more likely to break. Another study found that people who drank lime juice had lower levels of bone density. Kidney stones are a type of calcium deposit that can be painful and cause serious health problems. One study found that people who drank more than two glasses of lime juice per day had a higher risk of developing kidney stones. However, there is some concern that lime juice may be bad for your bones. Lime juice is a citrus fruit that is high in vitamin C.
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